Nobel Prize-Winning Science

Anti-Aging Skincare


Nitric Oxide Activating AGE-DEFIANCE SERUM

Up to 70 applications in each bottle.

Reduce Wrinkles, Fine Lines, Dullness, and Dark Spots with Pneuma Nitric Oxide’s N1O1.

As you grow older, your body slowly loses its ability to produce the anti-aging molecule nitric oxide. This causes dullness, blemishes, fine lines, and wrinkles on your skin and makes your skin look older. At Pneuma Nitric Oxide, we have been researching ways to counter nitric oxide reduction to get your skin looking fresh, bright, and youthful again. 

As a result, our expert, Dr. Nathan S. Bryan, developed our N1O1 serum—the solution to all your skin problems. Our Nitric Oxide Activating Serum with a dual-chamber delivery system eliminates the root cause of wrinkles and helps you revitalize your skin and rewind signs of aging.


Say Yes to Clear and Radiant Skin with NO!

Get visibility smooth skin and regain your confidence without any side effects. We unlocked the power of Nobel Prize-winning science to create a revolutionary advancement in age defiance. Our Nitric Oxide Activating Serum is clinically tested and recommended by doctors. Buy our product now and discover a whole new you!
home-banner-asset copy

Special Offer

Get 50% Off Our Flagship N1O1 Serum

Free Nitric Oxide Boosting Age Defiance Eye Cream!

30-Day Risk-Free Money-Back Guarantee

Free Domestic Shipping

Holding skin product in hand

Reduces Wrinkles

Visibly Smooth Skin
No Side Effects

Serum Bottle

N1O1 by Pneuma

Nitric Oxide Boosting AGE-DEFIANCE SERUM

Eye Cream Transparent

N1O1 By Pneuma

Claim Free Eye Cream With Serum Order

Order While Supplies Last!

Our Nitric Oxide Activating Serum is usually available only in clinics, but we have a limited period special offer to help you get them directly from us. Call us to place your orders and get 50% off on your purchase. You will also receive a Nitric Oxide Boosting Age Defiance Eye Cream worth $100 as a gift. Did we mention that there’s also a 30-Day Money-Back Guarantee? What are you waiting for? Order now to look and feel fabulous!
Skin product


(†Results May Vary)

My skin overall has a better texture and a healthier glow. I have never been very consistent with my beauty routine due to my busy schedule, but the results from Pneuma Nitric Oxide have inspired me to use the product regularly. I don’t want to stop using this product. It is the one beauty product I won’t skip. 

Suzanne S., 57


Being a guy, I don’t like using products that have a strong fragrance. Pneuma has very little. I get shaving burn daily. N1O1 by Pneuma helped soothe my irritated skin and gave me an airbrushed complexion. I’d recommend it to any guy who just wants to look better.

Robert M., 49

N1O1 Nitric Oxide Activating
Age-Defiance Serum including a FREE Eye Cream ($125 Value) & FREE Shipping!

MSRP $300.00 $150.00


SAVE 50%♢
Try a 30-day supply of N1O1  Nitric Oxide Activating Serum for just $150.00 plus a FREE Nitric Oxide Activating Eye Cream and FREE shipping and processing. You will receive one 30ml bottle with this purchase. One-time purchase. No automatic shipments!  Length of supply reflects daily application but typically includes 70 uses.

The N1o1 Money-Back Guarantee

There's nothing to lose, except Your wrinkles.

Skip to content