Circulation support
Nitric oxide plays a role in blood-vessel relaxation and healthy blood flow.








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Discover N1O1 dissolving lozenges for daily circulation support, with N.O. Beetz available as a drink-mix alternative.
60 lozenges per bottle · 2 lozenges daily
Nitric oxide is a signaling molecule involved in blood-vessel relaxation and healthy circulation. N1O1 offers two supplement formats: lozenges that dissolve in the mouth and N.O. Beetz powder mixed into water. Compare each product’s ingredients and directions, then choose the format that fits your routine.
Nitric oxide plays a role in blood-vessel relaxation and healthy blood flow.
Let the N1O1 lozenge dissolve slowly in your mouth, following your current bottle directions.
Explore N.O. Beetz below for a separate formula mixed into water. Read its own label and directions.
Build your routine, step by step. Follow the directions on each current package.
Place one lozenge in your mouth.
Move it slowly around the mouth. Allow approximately 5–6 minutes to dissolve.
Use one lozenge twice daily, 12 hours apart. Follow the directions on your current bottle.
Vitamin C (magnesium ascorbate), magnesium and the N1O1 proprietary blend are listed on the original product label. Review the full panel for declared amounts and other ingredients.
Amounts transcribed from the original N1O1 product page. Check the current Supplement Facts panel for serving size and Daily Values.
Mannitol , Microcrystalline Cellulose , Dextrin, Natural Flavors , Croscarmellose Sodium , Maltodextrin , Stearic Acid , Vegetable Stearate , Food Starch - Modified, Starch , Silica , Citric Acid
View the original label images in the gallery above. Your current package is the reference for the formula and directions.
Back to the product galleryOriginal N1O1 videos for this product. Choose a video to hear the explanation and see the routine.
Watch the original N1O1 demonstration.
Watch the original N1O1 demonstration.
Dr. Nathan S. Bryan’s work focuses on nitric oxide biochemistry. Explore the formulation, follow the directions and keep learning about the science behind your routine.
Hear from N1O1
Research references linked by N1O1 for this product. Individual studies have their own designs and populations; they are provided for further reading.
4.63 / 5.0 from 41 published customer reviews.
The essentials for Heart Health & Circulation.
N1O1 offers dissolving lozenges and N.O. Beetz drink mix. Each has its own ingredients, serving size and directions. The buy box on this page is for lozenges; explore N.O. Beetz below.
Place one lozenge in your mouth and move it slowly as it dissolves, approximately 5–6 minutes. N1O1 recommends one lozenge twice daily, 12 hours apart. Follow your current bottle directions.
Four bottles of the same N1O1 lozenge formulation, with 60 lozenges per bottle. The bundle is offered as buy three, get one free.
The original N1O1 directions recommend mixing one packet with 2–3 ounces of water and consuming immediately, once daily for adults. Follow the current package directions.
Stop use and ask a healthcare professional for advice. Follow the precautions on your current bottle.
Choose Subscribe in the buy box to see the current price and delivery schedule. The selling plan and selected quantity are included when you add the product to your cart. Review the subscription terms at checkout.
Free shipping applies to orders over $75 in the continental US. Read the current policy for eligibility, timing and return instructions.
Read shipping & return termsThese statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
1 bottle$59.98