The Science Of Age Defiance
CONFIDENCE BEGINS HERE.
The Science of Age-Defiance
Confidence Begins Here.
Visibly Smoother Skin. Clinically Proven.
Explore Our Range Of Age-Defiance Products
Shop Best Sellers
Backed By 20+ Years of Science, Clinical Studies, & Nobel Prize for Nitric Oxide Discovery
A REVOLUTIONARY ADVANCEMENT IN AGE Defiance
• Reduces Wrinkles & Fine Lines
• Corrects Dark Spots & Evens Skin Tone
• Improves Skin Texture & Clarity
• Increases Elasticity & Restores Moisture
• Creates Tighter, Smoother Skin
• Repairs Damaged Skin
Backed by 20 Years of Scientific Research and Peer-Reviewed Published Clinical Studies. View the clinical studies click here.
A recently published study in the Journal of Surgery by Gregory Chernoff, M.D., F.R.C.S.(C) demonstrated the successful use of N1O1 a topical Nitric Oxide serum on aging skin, acne, wound healing, and scar therapy. View the study here.
Dr. Bryan, CEO & Founder, has been a pioneering figure in the field of nitric oxide research for over 20 years. In addition to creating N1O1 by Pneuma Nitric Oxide, he is the holder of more than a dozen issued U.S. and International patents for breakthrough techniques that have revolutionized human physiology and disease management. The revolutionary N1O1 Nitric Oxide Activating Anti-Aging Serum is his next breakthrough patent.
THE AGE DEFIANCE Blog
Dr. Nathan S. Bryan has been involved in nitric oxide research for decades. His discoveries and product innovations have established him as an international leader in the nitric oxide field. PR Newswire AUSTIN, Texas, April 28, 2020 AUSTIN, Texas, April 28,...
KEY POINTS: Nitric oxide is free radical gas. It is produced endogenously and is synthesized from arginine by nitric oxide synthase. Nitric oxide mediates vasodilation, inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits...
Why do I get wrinkles on my face as I get older? Aging is an extremely complex process that affects the entire body. Recent scientific breakthroughs have shed light on this process and identified one of the primary factors in aging. It’s called Nitric Oxide. Naturally...
What real n1o1 users are Saying...
Michelle W., 49
My skin was dry, aging, lifeless, kind of dull. I needed to rejuvenate my skin but needed something simple, no deep regimens. My age spots diminished, so did the wrinkles around my mouth and smile lines, my skin plumped up. I felt it was working the minute I put it on. I felt a little bit of heat, which dissipated, and I felt it plumping my skin. My pores diminished, my makeup goes on smoother, my skin is brighter, rejuvenated, less fine lines, and wrinkles.
Cheyenne A., 19
Suzanne S., 57
Gia A., 45
I am using Pneuma currently, so that's how I know about it. It is simply the most transformative skincare product I've ever used!
Lora A, Dragon Tree Therapeutic, LLC
Robert M., 49
Being a guy, I don't like using products that have a strong fragrance. Pneuma has very little. I get shaving burn daily. Pneuma helped soothe my irritated skin and gave me an airbrushed complexion. I'd recommend it to any guy who just wants to look better
Laurie H., Owner & Co-Director, Facial Rejuvenation Center
The N1o1 Money-Back Guarantee
There's nothing to lose, except Your wrinkles.
Pneuma Nitric Oxide, LLC
2407 S. Congress
Suite E 134
Austin, TX. 78704
Developed and manufactured in the USA by Pneuma Nitric Oxide LLC.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat,
cure, or prevent any disease