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Unlock radiant, youthful skin with our expertly crafted skincare solutions for every skin type and concern.

Nitric Oxide from is gluten free

Gluten Free

Nitric Oxide from is GMO Free

GMO Free

Nitric Oxide from is sugar free

Sugar Free

Nitric Oxide from is lactose free

Lactose Free

Skin Care

Experience the breakthrough innovation in nitric oxide supplements, backed by the globally recognized expertise of Dr. Nathan S. Bryan. It’s more than a supplement; it’s a commitment to living fully, passionately, and healthily.

Integrating our nitric oxide supplements into your daily routine, you’re embracing a holistic approach to well-being. Whether it’s the energy to play with your grandchildren or the stamina for your favorite sport, our solutions are there to support you.

"This face cream is amazing! It's lightweight, non-greasy, and perfect for my sensitive skin. My complexion has never looked better."


Over 1,600 Five Star Reviews

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Your Skincare Solution

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    Advanced Anti-Aging: Combat fine lines and wrinkles for a youthful glow.

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    Deep Hydration: Maintain plump, moisturized skin all day long.

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    Environmental Protection: Shield your skin from harmful pollutants and UV rays.

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    Boosted Collagen: Enhance skin elasticity and firmness naturally.

How Our Products Work

Hydrates Deeply Protects Skin Boosts Collagen

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See the Transformation: Before & After


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1,000,000+ customers worldwide!

Don't just take our word for it

Over 1,600 five star reviews

4.9 average
776 reviews

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LOVE the combination of this serum! It tightened my face and helped keep my face looking its best. I truly loved it and it's worth every penny! I am 45+ and have become very purposeful with every serum and face cream I use these days. This was never oily, it never broke out my skin, and the results have been obvious! Thrilled with the results.

Berri Gormley

Age-Defiance Serum shop now

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Has amazing action on some long standing dried non-healing skin lesions. Also pale dry, corpse-like complexion looks alive again. Hoping with long-term use I’ll see more uniformity in color and tone. Moisturizes well but a follow up with another moisturizing product enhances it. Scent is somewhat reminiscent of when parched earth is damped by light rainfall, so not your typical fruitiness of common moisturizers.

Antoinette Simmons

Age-Defiance Face Cream shop now

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Martin W.

I like the texture, smell is very neutral, which i like, and it is filled completely to the top so be careful when taking off the lid, be ready to apply some. I have tried other N1O1 products and this is a great compliment and worth the price. after applying i could feel a slight tingling sensation, but seems to be working great to hydrate the area around my eyes. I am grateful there is a N1O1 store on amazon.

Age-Defiance Eye Cream shop now

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Pure Ingredients, Pure Results

We prioritize high-quality ingredients to ensure you look and feel your best. No shortcuts, no compromises just effective, reliable skincare.


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