How To Use
Achieve radiant skin and enhanced vitality with the N1o1 Dyno Duo —your essential solution for glowing, youthful skin and overall wellness. The Dyno Duo bundle is creating beauty from the outside (serum) and from the inside (lozenges). Optimize your nitric oxide production today and see your health transform right before your eyes.
N1o1 Nitric Oxide Activating Serum
1. Apply a single pump from each chamber to the palm of your hand, mix together and apply to the entire face and neck.
2. Allow to fully absorb 1-2 minutes before applying anything else.
3. Continue as a daily routine, applying morning and night to a clean face.
NOTE: Within a few seconds your face may turn a slight pink due to an increase in nitric oxide. This may last up to 5 minutes.
and for
N1o1 Nitric Oxide Lozenges
Take 1 Lozenge Twice a Day
Adults: Take 1 lozenge twice daily, 12 hours apart, on an empty stomach.
Learn More
Instructions: Place one lozenge in the mouth, moving it over the top of the tongue until fully dissolved. Swallow the saliva. Do not swallow the lozenge whole.
Why Dissolve the Lozenge?
N1O1 lozenges are designed to release Nitric Oxide as they dissolve in the mouth.
Safety and Storage Information
Consult your doctor before use if you are:
Pregnant or nursing
Taking medication
Using organic nitrates or phosphodiesterase inhibitors
Having difficulty swallowing
Diagnosed with a medical condition
Discontinue use if you experience dizziness or fainting.
Storage: Store in a dry place at room temperature. Keep the container tightly closed. Do not use if the seal is broken or missing. For adult use only. Keep out of reach of children.
Note: Supplements may naturally change color over time without affecting effectiveness.























Carolyn Frakes (verified owner) –
I’ve been using the Nitric Oxide Dyno Duo for a few months. I hadn’t noticed much of a difference until I went back to my aesthetician after a short break, and she remarked that my skin was looking fantastic! The Duo is now part of my daily routine!
Katy L. (verified owner) –
The Nitric Oxide Dyno Duo delivers a practical, two-pronged approach: internal support that aligns with steady energy and circulation, and a topical boost that visibly improves texture and radiance. For anyone looking to streamline wellness and skincare into one easy routine, this bundle is a strong, user-friendly option. Consistent use is key, but the payoff—smoother skin and heart health and wellness support from the inside—it’s totally worth it!
Lauren Mitchell (verified owner) –
As a nurse practitioner, I truly stand by these! I started the Dyno Duo to support my heart health, and I’m impressed. My resting heart rate is steadier on runs, and I feel more energized during the day. The serum is a bonus—my skin texture looks smoother and makeup sits better. It’s so easy: one lozenge twice a day and the serum morning and night. Noticeable results without a complicated routine.
Nicole R. (verified owner) –
The Dyno Duo gave me wins inside and out. I feel like that lozenges have really helped my mental clarity—I’m alert through afternoon meetings without an extra coffee. The serum is the real glow-up: my skin looks smoother and brighter, and fine lines around my mouth are softer. Several coworkers asked what I changed. I love that it’s simple—one lozenge twice a day and the serum morning and night—and it actually delivers.
Sara W. (verified owner) –
The Dyno Duo is a game changer. The lozenges are my secret weapon for staying sharp during long shifts, and the serum has completely transformed my skin. It’s smoother, more hydrated, and my coworkers keep commenting on how refreshed I look. Love that it’s so easy to incorporate into my routine.
Carrie (verified owner) –
These are my top two favorites from N1o1! I’ve been using the nitric oxide lozenges for over a year and absolutely love the health benefits they provide. Now, I’m giving my skin the same care with their serum, which is backed by numerous clinical studies. I especially love how you can see it working as my skin takes on a slight pink hue upon application—it’s an amazing product! There’s nothing else like it.
Melanie Y. (verified owner) –
I’ve been using N1o1 products for a few months now, and I’m so impressed with the results! The nitric oxide lozenges have been a game-changer for my overall health, and the serum is just as incredible. My skin feels healthier, smoother, and I love how you can actually see it working with a little pink glow indicating the increase in blood flow. Highly recommend giving these a try!
Gale Lin (verified owner) –
The Nitric Oxide Dyno Duo has completely simplified my routine. I love how it combines internal health support with a topical product that leaves my skin looking brighter and smoother. After just a few weeks, I’ve noticed a real difference in my energy levels and skin texture. It’s such an easy way to take care of both wellness and skincare at the same time.
amber johnson (verified owner) –
I love watching Dr. nathan’s videos about nitric oxide. I had no idea that my body could be depleting such a significant molecule as we get older. This dyno duo set is everything I need all in one – a daily supplement for my nutrition and an easy way to boost my skincare!
michelle bo (verified owner) –
I’m only 2 weeks in using this set but i think it’s working. i can’t feel the lozenges but just knowing i’m doing something to support my heart health as I age gives me better peace of mind. i like how light the serum goes on and my makeup sits on top.
Benjamin (verified owner) –
As a guy I don’t typically leave reviews for skincare products but Dr. Bryan is a genius. His nitric oxide lozenges have been a daily part of my routine for quite some time. After watching more videos, I decided to give the serum a try and I’m so glad I did. This is the only “beauty” routine I do.
Matt –
This bundle is a game changer. I love the energy boost that the lozenges give me and my wife loves the serum. She appreciates her smoother skin. Not going to lie…me too.