What is nitric oxide and why is it important?

Nitric oxide (NO) is a signaling molecule produced naturally in your body that plays a critical role in cardiovascular health, blood pressure regulation, immune function, and cellular communication. Production declines with age, making supplementation beneficial.

How do N1O1 nitric oxide lozenges work?

N1O1 lozenges dissolve on the tongue and deliver a patented nitric oxide formula directly through the oral mucosa, bypassing the digestive system for faster absorption. They help restore nitric oxide levels that naturally decline with age.

Who is Dr. Nathan S. Bryan?

Dr. Nathan S. Bryan is a world-renowned nitric oxide biochemist and the founder of N1O1. He has over 20 years of research in nitric oxide science, authored multiple books, and holds numerous patents in nitric oxide technology.

What are the benefits of nitric oxide supplements?

Nitric oxide supplements may support healthy blood pressure, improved circulation, cardiovascular health, enhanced athletic performance, immune function, cognitive health, and anti-aging at the cellular level.

N.O. Beetz is N1O1's beet-based nitric oxide supplement that harnesses the natural nitrate content of beets to boost nitric oxide production. Available individually or in a buy-3-get-1-free bundle.

Does N1O1 offer skincare products?

Yes, N1O1 offers a complete Age-Defiance Skincare System including an activating serum, face cream, eye cream, and gel cleanser — all formulated with nitric oxide technology to promote skin health and anti-aging.

How should I take N1O1 lozenges?

Place one lozenge on your tongue and allow it to fully dissolve. Do not chew or swallow whole. For best results, use daily as directed on the product label.

Are N1O1 products backed by science?

Yes, N1O1 products are developed by Dr. Nathan S. Bryan based on decades of peer-reviewed nitric oxide research. The formulations are protected by multiple patents and supported by clinical data.

What is CardioSmile toothpaste?

CardioSmile is N1O1's nitric oxide-boosting toothpaste that supports oral and cardiovascular health. Unlike conventional toothpastes that contain antiseptics that kill beneficial oral bacteria needed for nitric oxide production, CardioSmile promotes a healthy oral microbiome.

Do you offer bundle deals?

Yes, N1O1 offers several bundles including the Nitric Oxide Booster Bundle, Anti-Aging Bundle, Dyno Duo, Couples Performance Bundle, Body & Mind Essentials, and buy-3-get-1-free deals on lozenges and N.O. Beetz.

Is N1O1 suitable for athletes?

Yes, nitric oxide plays a key role in blood flow and oxygen delivery to muscles. Many athletes use N1O1 lozenges to support performance, recovery, and endurance.

What is the Nitric Oxide Oral Wellness Duo?

The Oral Wellness Duo combines N1O1 nitric oxide lozenges with CardioSmile toothpaste for comprehensive oral and cardiovascular support through nitric oxide restoration.

Do you ship internationally?

Shipping details and policies are available on the N1O1 website. Visit the Shipping and Returns Policy page for the most current information.

Can nitric oxide help with aging?

Research shows nitric oxide production declines with age, contributing to cardiovascular issues, reduced energy, and skin aging. Restoring NO levels through supplementation may help address these age-related changes.

Where can I learn more about nitric oxide?

N1O1 offers extensive educational resources including the Nitric Oxide Knowledge Base, Nitric Oxide Glossary, featured podcasts, press features, and Dr. Bryan's books 'The Secret of Nitric Oxide' and 'Nitric Oxide Nutrition'.

Sale!

N1o1 Nitric Oxide Age-Defiance Skincare System
Rated 4.91 out of 5
Original price was: $299.92.Current price is: $269.92. — available on subscription Add to cart
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Nitric Oxide Dyno Duo
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Original price was: $179.96.Current price is: $161.96. — or subscribe to save 10% Add to cart
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Nitric Oxide Booster Bundle
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Original price was: $129.96.Current price is: $116.96. — or subscribe to save 10% Add to cart
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Nitric Oxide Anti-Aging Bundle
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Original price was: $159.96.Current price is: $143.96. — available on subscription Add to cart
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Couples Performance Bundle
Rated 4.91 out of 5
Original price was: $129.96.Current price is: $116.96. — available on subscription Add to cart

Featured Podcasts

N1o1 Nitric Oxide Age-Defiance Skincare System

Nitric Oxide Dyno Duo

Nitric Oxide Booster Bundle

Nitric Oxide Anti-Aging Bundle

Couples Performance Bundle

CardioSmile Nitric Oxide Boosting Toothpaste

N1o1 Nitric Oxide Lozenges

N1o1 Featured Podcasts

Why Big Pharma Hates Nitric Oxide (And How to Use It Anyway): The Dave Asprey Podcast

No.1 Nitric Oxide Expert: This is the anti-aging cure no one is talking about!: Diary of a CEO Podcast

Increase Nitric Oxide: Fix Blood Pressure & Inflammation Naturally – Dr. Nathan Bryan on The Primal Podcast with Rina Ahluwalia

How Mouthwash, Fluoride, and Antacids are Slowly Destroying Your Health Nathan Bryan, PhD on The Genius Life with Max Lugavere

Nitric Oxide: How To Naturally Lower Blood Pressure & REDUCE Inflammation: Dr. Nathan Bryan on The Dhru Purohit Podcast

Nitric Oxide and Functional Health on The Empowering Neurologist with Dr. David Perlmutter

All N1o1 Podcasts

Ageless and Timeless with Michelle Hughes

Dr. Nathan Bryan on Executive Connect’s Inner Health Series on the Executive Connect Podcast

A MoMent of Xen Ep228 Live iHeart Radio Show / 710 WOR The Voice of New York

Nitric Oxide Explained: Dr. Nathan Bryan on Aging, Alzheimer’s, and Performance: Ever Forward Radio

Dr. Nathan Bryan on The Dan Astin-Gregory Podcast

Why Big Pharma Hates Nitric Oxide (And How to Use It Anyway): The Dave Asprey Podcast

Dr Nathan Bryan – World Expert In Nitric Oxide Research: TheMedEmpire.Health Podcast

The Molecule of Life: Why Nitric Oxide is Key to Your Health – Dr. Nathan Bryan Explains: Linda Stephens Fit Podcast

Demolish Alzheimer’s: Nitric Oxide Breakthrough Revealed: Khan Klinics Podcast

No.1 Nitric Oxide Expert: This is the anti-aging cure no one is talking about!: Diary of a CEO Podcast

The Molecule That Could Save Your Life: Dr. Nathan Bryan

Episode 136: “Dr. Nathan Bryan”