If you are a returning customer, please LOGIN before you shop.


$345.00 available on subscription


N1o1 products are perfectly formulated to work together to create a powerful skincare regimen that’s clinically tested and doctor recommended. It’s a simple 4-step system that provides real results that will change the way you see yourself.  


The One Skincare System That Makes All Skin Cells Act Younger

Skin cells need Nitric Oxide to function. Unfortunately, as we age, Nitric Oxide production drops and skin cells begin to lose their ability to retain moisture and nutrients. 

Using the Age-Defiance Eye Cream and Face Cream along with the Nitric Oxide Activating Serum on skin that’s been prepped with the Exfoliating Gel Cleanser, boosts and activates your body’s own Nitric Oxide production. With adequate Nitric Oxide available, your skin cells will act more like they did in your 20s.

Use the Anti-Aging Skincare System to: 

• Reduce wrinkles and fine lines

• Correct dark spots

• Improve skin texture and clarity

• Even skin tone

• Increase elasticity

• Restore moisture

• Create tighter, smoother skin

• Repair damaged skin

Statements made have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Due to popular demand, limit 1 per order!

SKU: NEC15-1 Categories: , , ,


Don’t Just Look Younger. Feel Younger With the ONLY Nitric Oxide Activating Skincare System

N1o1 Nitric Oxide Activating Age-Defiance System includes four products that are changing the way we approach skincare. These revolutionary skincare products are specially formulated to provide a surge of Nitric Oxide that supports skin cells. Other powerful, proven ingredients are combined to further enhance the function of skin so that you look and feel more like yourself as you age.

All N1o1 products are made to work together to create a skincare system that improves skin down to a cellular level to enhance what you see on the surface.

Pneuma Oxygenating Age-Defiance Gel Cleanser

Our exfoliating gel cleanser gently cleans with plant extracts and Alpha-Hydroxy Acid (AHA). It also contains a blend of ingredients that encourages cellular turnover, oxygenates skin cells, protects and soothes the skin.

N1o1 Nitric Oxide Activating Age-Defiance Serum

N1o1 Nitric Oxide Activating Serum dramatically reverses the signs of N.O. depletion by utilizing Nobel Prize-winning research. It’s the FIRST skincare product to use the “Miracle Molecule” Nitric Oxide to stimulate collagen production and restore the youthful flow of oxygen, hydration, and nutrients to your skin cells.

Nitric Oxide Boosting Age-Defiance Eye Cream

Four amazing anti-aging ingredients come together in N1o1 Nitric Oxide Boosting Age-Defiance Eye Cream. It targets problem areas around your eyes to address wrinkles, circles, and laxity down to a cellular level.

Nitric Oxide Boosting Age-Defiance Face Cream

N1o1 Nitric Oxide Boosting Age-Defiance Face Cream is specially formulated with three anti-aging ingredients that target age-related skin issues and support N.O. production in a way that no other face cream does.

Statements made have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Additional information

Weight 3.0 oz

How To Use


  1. Apply to damp skin.
  2. Massage until a creamy, moisturizing foam develops.
  3. Rinse off thoroughly.


  1. Apply a single pump from each chamber to the palm of your hand, mix together and apply to the entire face and neck.
  2. Allow to fully absorb 1-2 minutes before applying other products.
  3. Continue as a daily routine, applying morning and night to a clean face.

NOTE: Within a few seconds your face may turn a slight pink due to an increase in Nitric Oxide. This may last up to 5 minutes.


  1. Using clean hands, apply cream to the eye area in the AM and PM.
  2. Dab gently around the eyes being careful not to get any product in the eyes.
  3. Allow cream to fully absorb 1-2 minutes. 


  1. Use after cleaning and applying the Nitric Oxide activating serum.
  2. Apply with clean hands in the AM and PM.
  3. Allow to fully absorb 1-2 minutes.


Nitric Oxide Activating ANTI-AGING SERUM Water, Ascorbic acid, Polysorbate 20, hydroxyethylcellulose, sodium nitrite, d-Tocopheryl Acetate, dehydroacetic acid, benzyl alcohol, sodium sulfite, sodium metabisulfite, tetrasodium EDTA

Nitric Oxide Boosting AGE-DEFIANCE FACE CREAMWater, Vitis Vinifera (Grape) Seed Oil, Cetearyl Alcohol, Glyceryl Stearate SE, Squalane, Ceteareth-20, Glycerin, Sodium Nitrite, Magnesium Aluminum Silicate, Sodium PCA, Sodium Hyaluronate, Butylene Glycol, Polyacrylamide, Palmitoyl Tripeptide-1, Lecithin, Acetyl Glutamine, Palmitoyl Tetrapeptide-7, sh-Oligopeptide-1, sh-Oligopeptide-2, Arnica Montana Flower Extract, Cetyl Esters, Humulus Lupulus (Hops) Extract, sh-Polypeptide-1, sh-Polypeptide-9, Equisetum Hyemale Extract, sh-Polypeptide-11, Pinus Strobus Cone Extract, Lecithin, Bacillus/Folic Acid Ferment Filtrate Extract, Hydrogenated Ethylhexyl Olivate, Hydrogenated Olive Oil Unsaponifiables, Citrus Limon (Lemon Bioflavonoids) Peel Extract, Rosmarinus Officinalis (Rosemary) Extract, C13-14 Isoparaffin, Phenoxyethanol, Cetyl Alcohol, 1,2-Hexanediol, Caprylyl Glycol, Laureth-7, Polysorbate 20, Carbomer, Titanium Dioxide

Nitric Oxide Boosting AGE-DEFIANCE EYE CREAMWater, Helianthus Annuus (Sunflower) Seed Oil, Cetearyl Alcohol, Glyceryl Stearate SE, Squalane, Dimethicone, Garcinia Indica Seed Butter, Ceteareth-20, Glycerin, Sodium Nitrite, Magnesium Aluminum Silicate, Sodium PCA, Palmitoyl Tripeptide-5, Coconut Alkanes, Propanediol, Polyacrylamide, Sodium Hyaluronate, Tremella Fuciformis (Mushroom) Extract, Palmitoyl Tripeptide-1, Dicaprylyl Ether, N-Hydroxysuccinimide, Camellia Sinensis Leaf Extract, Cetyl Alcohol, Palmitoyl Tetrapeptide-7, Cetyl Esters, Dunaliella Salina Extract, Cocos Nucifera (Coconut) Oil, C13-14 Isoparaffin, Cucumis Sativus (Cucumber) Fruit Extract, Biosaccharide Gum-1, Ceteareth-25, Steareth-20, Laureth-7, Behenic Acid, Phenoxyethanol, Cholesterol, Cocos Nucifera (Coconut) Liquid Endosperm, Ceramide NP, Ceramide NS, Ceramide EOS, Ceramide EOP, Ceramide AP, Chrysin, Cocos Nucifera (Coconut) Fruit Juice, Caprooyl Phytosphingosine, Caprooyl Sphingosine, Caprylyl Glycol, Panthenol, Coco-Caprylate/Caprate, Lecithin, Titanium Dioxide.

Pneuma Age-Defiance EXFOLIATING GEL CLEANSERWater, Ammonium Lauryl Sulfate, Potassium Cocoate, Glycerin, Hydroxyethylcellulose, Polysorbate 20, Glycolic Acid, Lactic Acid, Citric Acid, Tartaric Acid, Malic Acid, Passiflora Edulis Fruit Extract, Ananas Sativus (Pineapple) Fruit Extract, Vitis Vinifera (Grape) Fruit Extract, Aloe Barbadensis Leaf Juice, Algae Extract, Ascorbic Acid, Camellia Oleifera Leaf Extract, Lonicera Caprifolium (Honeysuckle) Flower Extract, Lonicera Japonica (Honeysuckle) Flower Extract, Propylene Glycol, Cola Acuminata Seed Extract, Alcohol Denat., Tetrasodium EDTA, Fragrance.


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.