Age-Defiance Face Cream

A face cream with peptides, growth factors, humectants and nourishing lipids. Finish your morning and evening skincare routine with a moisturizer designed by Dr. Nathan S. Bryan.

1.75 oz / 50 g

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1 jar · $79.98 today

$75

Free shipping over $75 in the continental US.

Meet the people behind your routine

  • Developed by Dr. Nathan Bryan
  • Peptides & hydration
  • Morning & night

Finish with lasting hydration.

A face cream with peptides, growth factors, humectants and nourishing lipids. Finish your morning and evening skincare routine with a moisturizer designed by Dr. Nathan S. Bryan.

Hydrate

Glycerin, sodium PCA and sodium hyaluronate are included in the formula.

Condition

Grape seed oil and squalane support a soft, moisturized skin feel.

Complete your routine

Use after the cleanser and serum on clean, dry skin.

Nitric Oxide Age-Defiance Face Cream

Your morning and evening finish.

Build your routine, step by step. Follow the directions on each current package.

  1. Prepare

    Begin with clean, dry skin.

  2. Apply

    Apply the cream to the face as directed on the current package, morning and night.

  3. Store

    Keep in a cool, dark place and use before the expiration date on the package.

Inside the formulation.

Sodium nitrite, a peptide complex, growth factors including sh-oligopeptide-1, glycerin, sodium PCA, sodium hyaluronate, grape seed oil and squalane. See the complete ingredient list below.

Complete ingredient list

Water, Vitis Vinifera (Grape) Seed Oil , Cetearyl Alcohol , Glyceryl Stearate SE , Squalane , Ceteareth-20 , Glycerin , Sodium Nitrite , Magnesium Aluminum Silicate , Sodium PCA , Sodium Hyaluronate , Butylene Glycol , Polyacrylamide , Palmitoyl Tripeptide-1 , Lecithin , Acetyl Glutamine , Palmitoyl tetrapeptide-7 , sh-Oligopeptide-1 , sh-Oligopeptide-2 , Arnica Montana Flower Extract , Cetyl Esters , Humulus Lupulus (Hops) Extract , sh-Polypeptide-1 , sh-Polypeptide-9 , Equisetum Hyemale Extract , sh-Polypeptide-11 , Pinus Strobus Cone Extract , Lecithin, Bacillus/Folic Acid Ferment Filtrate Extract , Hydrogenated Ethylhexyl Olivate , Hydrogenated Olive Oil Unsaponifiables , Citrus Limon (Lemon Bioflavonoids) Peel Extract , Rosmarinus Officinalis (Rosemary) Extract , C13-14 Isoparaffin , Phenoxyethanol , Cetyl Alcohol , 1,2-Hexanediol , Caprylyl Glycol , Laureth-7 , Polysorbate 20 , Carbomer , Titanium Dioxide .

Read the product label

View the original label images in the gallery above. Your current package is the reference for the formula and directions.

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Watch. Learn. Make it a routine.

Original N1O1 videos for this product. Choose a video to hear the explanation and see the routine.

N1o1 Nitric Oxide - Nitric Oxide Boosting Face Cream with Susan Shaffer

Watch the original N1O1 demonstration.

N1o1 Age-Defiance Face Cream - Unlock Youthful Skin

Watch the original N1O1 demonstration.

Developed by the scientist behind N1O1.

Dr. Nathan S. Bryan’s work focuses on nitric oxide biochemistry. Explore the formulation, follow the directions and keep learning about the science behind your routine.

Hear from N1O1
Dr. Nathan S. Bryan, the scientist behind N1O1

What customers report.

4.85 / 5.0 from 13 published customer reviews.

Questions before you start?

The essentials for Age-Defiance Face Cream.

When should I use the cream?

Apply morning and night on clean, dry skin.

Can it be used with the N1O1 serum?

The original product page pairs it with the Gel Cleanser, Activating Serum and Eye Cream. Let the serum absorb before layering other products.

How should I store it?

Keep the cream in a cool, dark place and use it before the expiration date printed on the package.

How do subscriptions work?

Choose Subscribe in the buy box to see the current price and delivery schedule. The selling plan and selected quantity are included when you add the product to your cart. Review the subscription terms at checkout.

What about shipping and returns?

Free shipping applies to orders over $75 in the continental US. Read the current policy for eligibility, timing and return instructions.

Read shipping & return terms

1 jar$79.98

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