I used N1o1 for three months and my skin never looked better. Foolishly I stopped. Within two days, I noticed my skin texture had changed and the radiance of my skin became dull again. I started N1o1 again and my skin looks great.

— Mary T

I tried this and wasn’t sure what to expect. It has been easy to roll into my routine. I take the lozenge usually in the morning and then the powder before my workout. Game changer! I can go longer and also not feel so fatigued too. I won’t go without it now. I feel great!

— Annie J

Sexual dysfunction is often the earliest indicator of nitric oxide deficiency, affecting both men and women. Achieving an erection relies on proper vasodilation, a process dependent on adequate nitric oxide levels in the body.

— Dr. Nathan S Bryan

Nitric Oxide Booster Bundle

(27 customer reviews)

N1o1 Nitric Oxide Lozenges + N.O. Beetz

Support your health with the ultimate combo for a nitric oxide boost and natural energy. Developed by Dr. Nathan Bryan, Biomedical Scientist.

Maximum of 1 bundle per order due to popular demand

$116.96 or subscribe to save 10%

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60-Day Guarantee

100% Satisfaction Guarantee

Try the bundle for 60 days, risk-free! Not satisfied with your results? It’s on us!

Stronger. Healthier.
More Energized.

Our body thrives on strong circulation, peak endurance, and optimal performance. But as you age, nitric oxide production declines—leading to lower energy, sluggish stamina, and even weaker blood flow where it matters most.

That’s why we created the Nitric Oxide Booster Bundle—a powerhouse duo designed to boost nitric oxide levels, circulation, and energy so you can perform at your best every day—in the gym, in the office, and beyond.


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“The loss of nitric oxide production is recognized as the earliest event in the onset and progression of most, if not all, chronic diseases, including the number one killer of men and women worldwide—cardiovascular disease.”

—Dr. Nathan S. Bryan
International Expert in Nitric Oxide Biochemistry and Physiology

Additional information

Weight 8 oz

NO & Health

Dr. Nathan Bryan Talks Nitric Oxide on FOX & FRIENDS

Dr. Nathan Bryan joins FOX & FRIENDS to discuss the critical role of nitric oxide in overall health, energy, and longevity.

As a leading expert in the field, Dr. Bryan breaks down how this essential molecule supports circulation, heart health, brain function, and immune support—and why so many people may be unknowingly deficient.


Why Nitric Oxide is Essential for Your Health

The combination of N1o1 Lozenges and N.O. Beetz helps restore nitric oxide naturally—giving your body the fuel it needs to power through workouts, workdays, and beyond.

Boost Blood Flow Circulation

Boost Blood Flow & Circulation

Enhances oxygen delivery for better energy, faster recovery, and improved overall performance.

Sharpen Brain Function

Sharpen Brain Function

Supports memory, focus, and cognitive clarity by optimizing your Nitric Oxide levels.

Maximize Workout Endurance

Maximize Workout Endurance

Reduces fatigue, increase stamina, and fuel your muscles for peak performance.

Support Heart Health

Support Heart Health

Promotes healthy blood pressure, circulation, and overall cardiovascular function.

Unlock Full Body Wellness

Unlock Full-Body Wellness

Improves sleep, immunity, and vitality with Nitric Oxide’s powerful benefits.

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Elevate Mood & Energy

Feel more vibrant and energized with the natural boost Nitric Oxide provides.

What's Inside?

What's Inside the Bundle?

Final

N1o1 Nitric Oxide Lozenges (60 Lozenges – $59.98 value) – Dissolves in your mouth to rapidly boost nitric oxide, supporting stamina, circulation, and muscle recovery.

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N.O. Beetz (30 Packets – $69.98 Value) – Fermented beetroot that is oxalate-free, featuring patented PEAK ATP® and electrolytes to sustain nitric oxide production for long-lasting energy & endurance.

All for just $124.96. You’re saving $5.00!

Benefits

N1o1 Clinically Backed Benefits Nitric Oxide Lozenges

Timeline of Physiological Effects Induced by a Nitric Oxide Lozenge

Discover what’s happening in your body when you use a nitric oxide lozenge, from its physiological effects to how it quietly supports your overall health—even if you can’t feel it.
 

12 Seconds – Carotid arteries begin to dilate, increasing blood flow to the brain.
1 Minute – Blood vessels dilate, enhancing circulation throughout the body.
5 Minutes – Notice a 2.1% boost in exercise performance.
10 Minutes – Carotid arteries dilate by 13%, leading to a 34% increase in blood flow to the brain and body.
20 Minutes – For individuals with elevated blood pressure (130-139/80-89 mmHg), systolic and diastolic blood pressure drops by 5-6 mmHg.
20-30 Minutes – Blood vessels become more flexible and compliant, improving vascular function by 20% and reducing arterial strain.
60 Minutes – Elevated blood pressure drops further by 8-10 mmHg, with some cases seeing reductions of up to 50-60 mmHg for extremely high readings.

n1o1 nitric oxide booster bundle why you will love

4 HoursEndothelial function improves by 15-25%, boosting natural nitric oxide production.
2 Weeks – Blood flow regulation improves, enhancing mitochondrial function and exercise capacity.
3 Weeks – Reduced oxidative stress and inflammation.
1 Month – Blood pressure in pre-hypertension and hypertension patients decreases by 12 mmHg systolic and 6 mmHg diastolic, triglycerides drop by 27%, and cardiovascular health improves.
6 Months – Existing arterial plaque stabilizes and begins to regress by 11%; endothelial function normalizes.
9 Months – Kidney function improves, protein excretion decreases, and cardiac function strengthens, including reduced cardiac hypertrophy.
12 Months – Arterial health improves, telomeres stabilize, and antioxidant defenses combat post-meal oxidative stress and inflammation. Cognitive gains include better verbal memory and problem-solving skills.

Experience the comprehensive benefits of N1o1 Nitric Oxide Lozenges and transform your cardiovascular health at every stage.

N1o1 Clinically Backed Benefits N.O. Beetz 1

Timeline of Benefits with N.O. Beetz

Discover how N.O. Beetz works to support your health step by step:  
 
Within Minutes – Blood vessels begin to dilate, improving circulation and oxygen delivery.  
Within Hours – Enhanced nitric oxide levels lead to better energy, stamina, and focus.  
Within Weeks – Consistent use supports cardiovascular health, reduced oxidative stress, and improved endurance.  
Within Months – Long-term benefits include stabilized blood pressure, reduced arterial plaque, more mitochondria per cell producing more energy more efficiently and improved overall vitality.  

Experience the Power of N.O. Beetz

Transform your health and performance with N.O. Beetz, the natural, science-backed solution for boosting nitric oxide levels.

Directions

How Each Product Works

Nitric Oxide Daily Circulatory and Heart Health Support Lozenges by Dr. Nathan Bryan

Take One Nitric Oxide Lozenge Twice a Day to Undo Years of Damage

Place one lozenge in the mouth, moving the tablet around over the top of the tongue as it dissolves. Once the tablet has fully dissolved, swallow the remaining saliva.

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Take One Packet of N.O. Beetz a Day to Support Your Daily Workout

Pour one packet of N.O. Beetz into 2-3 ounces of water. Mix together to fully dissolve and consume immediately as a shot. Take as a pre-workout or whenever you need an added boost of energy.


It is ideal to space out the dosing of lozenges and N.O. Beetz.

Ingredients

OUR KEY INGREDIENTS

Natural & Potent ingredients
For enhanced nitric oxide production & better overall health

Together, these ingredients boost nitric oxide production, enhance circulation, boost energy, and support overall vitality, leaving you energized, focused, and thriving.

N1O1 Nitric Oxide Lozenges
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N1o1

Proprietary Blend
Magnesium Ascorbate and Sodium Nitrite optimizes nitric oxide production.

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NO2U

Proprietary Blend
Fermented Beet Root Powder that is oxalate-free, D-Ribose, and PEAK ATP®.

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PEAK ATP®

This patented ingredient fuels your muscles at the cellular level to optimize blood flow and stamina.

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Electrolytes

Helps maintain hydration, muscle function, and nerve signaling for sustained energy and peak performance.

FAQs

What is Nitric Oxide?
Nitric Oxide (NO) is a molecule that helps relax and widen blood vessels, improving circulation, oxygen delivery, and overall cardiovascular health. It also supports energy levels, endurance, and cognitive function.

N1o1 Nitric Oxide Lozenges – Instant Circulation & Energy Boost

  • Enhances oxygen & nutrient delivery to muscles and organs
  • Supports heart, brain, and circulatory health
  • Boosts stamina & endurance—so you can perform at your best
  • Easy, on-the-go lozenges—just dissolve and go!

N.O. Beetz harnesses the power of specially fermented beetroot powder to naturally elevate your body’s nitric oxide levels. By improving circulation, it promotes better energy and overall wellness—offering a gentle, sustained boost without the jitters or crash of stimulant-packed energy drinks.

Take One Nitric Oxide Lozenge Twice a Day to Undo Years of Damage

Place one lozenge in the mouth, moving the tablet around over the top of the tongue as it dissolves. Once the tablet has fully dissolved, swallow the remaining saliva.

Take One Packet of N.O. Beetz a Day to Support Your Daily Workout
Pour one packet of N.O. Beetz into 2-3 ounces of water. Mix together to fully dissolve and consume immediately as a shot. Drink 10 minutes before exercising or whenever you need an added boost of energy.


*It is ideal to space out the dosing of lozenges and N.O. Beetz.

Safety and Storage Information

Consult with your doctor before use if you are:

Pregnant
Nursing
Taking medication
Taking organic nitrates
Taking phosphodiesterase inhibitors
Having difficulty swallowing
Diagnosed with a medical condition
Discontinue use if you experience dizziness or fainting, which could be the result of low blood pressure.

N1o1 should be stored in a dry place that’s kept at room temperature. Keep the container tightly closed at all times and never use if the clear seal is broken or missing prior to purchase. N1o1 is for adult use only. Always store in a place that is out of the reach of children.

The supplements may change color over time naturally, but this in no way alters the

Many users report increased energy and better circulation within days. However, consistent use over a few weeks yields the best long-term benefits.

Natural & Potent ingredients for enhanced nitric oxide production & better overall health.

N1o1 Nitric Oxide Lozenges
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N.O. Beetz
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Dr. Bryan

About Dr Nathan Bryan

MEET THE FOUNDER

Dr. Nathan Bryan: A Leading Authority on Nitric Oxide

Dr. Nathan S. Bryan is an international leader in molecular medicine and nitric oxide biochemistry. Dr. Bryan’s discoveries have led to product and technology innovations that have improved patient care worldwide.

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A Pioneer in Nitric Oxide Science

With over 20 years of research in cardiovascular health and molecular medicine, Dr. Bryan is one of the world’s foremost experts on Nitric Oxide’s role in human health.

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Clinically Backed & Scientifically Proven

His discoveries have shaped the field of Nitric Oxide therapy, leading to cutting-edge solutions like the N1o1 Nitric Oxide Lozenges and N.O. Beetz you’re about to experience.

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On a Mission to Improve Lives

Dr. Bryan is dedicated to helping people unlock their body’s full potential through the power of Nitric Oxide—so they can live longer, healthier, and more vibrant lives.

Studies

[1] Nitric-oxide supplementation for treatment of long-term complications in argininosuccinic aciduria
PubMed
Sandesh C S Nagamani, Philippe M Campeau, Oleg A Shchelochkov, Muralidhar H Premkumar, Kilian Guse, Nicola Brunetti-Pierri, Yuqing Chen, Qin Sun, Yaoping Tang, Donna Palmer, Anilkumar K Reddy, Li Li, Timothy C Slesnick, Daniel I Feig, Susan Caudle, David Harrison, Leonardo Salviati, Juan C Marini, Nathan S Bryan, Ayelet Erez, Brendan Lee
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
Download the PDF

[2] The oral microbiome, nitric oxide and exercise performance
PubMed
Nathan S Bryan, Mia C Burleigh, Chris Easton
Institute for Clinical Exercise and Health Science, University of the West of Scotland, Blantyre, UK
Download the PDF

[3] Functional Nitric Oxide Nutrition to Combat Cardiovascular Disease
PubMed
Nathan S Bryan
Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Alkek Building for Biomedical Research R-850, Houston, TX, 77030, USA
Read the Study

[4] Nitric oxide enhancement strategies
PubMed
Nathan S Bryan
Department of Molecular & Human Genetics, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA
Download the PDF

[5] Oral nitrite therapy improves vascular function in diabetic mice
PubMed
Amy L Sindler, Kimberly Cox-York, Lauren Reese, Nathan S Bryan, Douglas R Seals, Christopher L Gentile

  • Department of Integrative Physiology, University of Colorado, Boulder, Boulder, CO, USA
  • Department of Health and Human Physiology, University of Iowa, Iowa City, IA, USA
  • Department of Food Science and Human Nutrition, Colorado State University, Fort Collins, CO, USA
  • Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA
  • Department of Integrative Physiology, University of Colorado, Boulder, Boulder, CO, USA
  • Department of Food Science and Human Nutrition, Colorado State University, Fort Collins, CO, USA

Read the Study

27 reviews for Nitric Oxide Booster Bundle

  1. Annie J.

    I tried this and wasn’t sure what to expect. It has been easy to roll into my routine. I take the lozenge usually in the morning and then the powder before my workout. Game changer! I can go longer and also not feel so fatigued too. I won’t go without it now. I feel great!

  2. Derrick

    Nothing but good things to say about these products. When I first got them I took the drink powder before heading out on a run. It was amazing. I felt like I was running on a new pair of legs that were 20 years younger. It was amazing! Definitely recommend!

  3. Denise

    I am a huge fan of the N1o1 serum and lozenges and N.O. Beetz! So glad I learned about nitric oxide and its importance in helping with blood pressure and cardiovascular health. As a 66-year-old woman, the serum has kept my face and neck looking younger than I am. As an avid athlete, the N.O. Beetz is my go-to before workouts to give me a boost of energy and important electrolytes. Fan forever of this company and its work!

  4. Jennifer C.

    The lozenges are a game changer. I definitely feel the difference with and without them. The NO Beetz is a great product I began using as a pre-workout and love it!

  5. Stephanie

    Have fallen in love with how I feel after using NO Beetz! Will definitely be ordering again.

  6. Jason C.

    I really love this bundle!!!!!!! The lozenges helped maintain my blood pressure and I get better sleep. Since I bike to work, the N.O. Beetz helps a lot especially when I am going back home. After all the days work, you get that extra boost to make it home and still have energy for daddy duties.

  7. Justin B

    My workouts have been the best I’ve had in a long time since I started taking this bundle. I take the NO Beetz in the morning and evening, and a lozenge before my workouts. I can feel the difference in my system. My stamina is improved. I can workout longer and harder.

  8. Simon R

    I’ve been taking the Lozenges for a few months and decided to try the Beetz when I saw this bundle. The products together are a perfect one-two punch, and I have noticed a dramatic increase in energy. Definitely worth the subscription.

  9. Heather

    I’ve been using the lozenges and beetz bundle consistently and the increase in energy is noticeable at 53 compared to my friends who don’t supplement with nitric oxide. I have energy to get through the work day while co workers are sluggish. The serum has also completely faded my brown spots on my face and chest. Amazing products!

  10. Ellie

    Game changer! I’ve never felt this good on a supplement. The N1O1 Booster Bundle gives me instant energy, better circulation, and real endurance during workouts. Blood pressure has improved, my hands stay warm, and I recover faster. The lozenges work fast—no gut issues like arginine powders. Clean, effective, and exactly what my body needed. Highly recommend!

  11. Courtney P

    I’ve been personally using and recommending Dr. Bryan’s nitric oxide products for over five years, and the results have been consistently outstanding. The synergistic effect of the two-product combination significantly enhances tissue oxygenation, which in turn supports improved cognitive function, greater stamina during physical activity, and healthier blood pressure levels. I confidently recommend these products to my general patient population, as they deliver a vital molecule—nitric oxide—that plays an essential role in numerous foundational biological processes.

  12. Bob Nickell

    Easy to fit into my routine—lozenge in the morning, Beetz before a workout—and suddenly I have more endurance and less fatigue.

  13. Andrew Lee

    took the powder before my run and felt like I had a new pair of legs—stronger and more energized. Highly recommend

  14. Gary Angel

    At 66, I feel younger and sharper. My skin looks great, my workouts are better, and my heart feels happier.

  15. Barbara Banks

    My bike commute home used to drain me, but with this bundle I still have energy for family time. Super noticeable—and I sleep better too

  16. Bella Berns

    Instant energy and improved circulation—I feel more alive during workouts, my hands stay warm, and recovery is faster. No weird supplements needed

  17. Mitchell

    I’ve been using the Nitric Oxide Booster Bundle for a few weeks now, and the difference in how I feel is incredible. My circulation has noticeably improved—I no longer experience the cold hands and feet I used to. I’ve also felt a boost in my overall cardiovascular health; climbing stairs and staying active feels so much easier. Incorporating the bundle into my daily routine couldn’t be simpler. I take a lozenge in the morning and the N.O. Beetz powder before my workout—it’s quick, effective, and has become a natural part of my day. I feel healthier, more energized, and confident that I’m supporting my heart in the best way possible. Highly recommended!

  18. Charlotte B.

    The Nitric Oxide Booster Bundle has completely transformed my days! From the first week, I felt an incredible boost in energy and mental clarity, making my workdays so much more productive. The simplicity of taking a lozenge in the morning and mixing the powder before workouts fits seamlessly into my routine. I feel sharper, more focused, and ready to tackle anything—all thanks to this amazing combo.

  19. Jordan T.

    As a fitness enthusiast, I’m always on the lookout for products that can push my workouts to the next level—and the Nitric Oxide Booster Bundle has done just that. The clean ingredients give me peace of mind, knowing I’m fueling my body with something healthy and effective. What really stood out for me was the stamina boost—my endurance during workouts has improved significantly. I’m able to power through high-intensity sessions and recover much faster afterward. Whether it’s the lozenges or the N.O. Beetz powder, both have become staples in my daily routine. This bundle has completely revolutionized the way I approach my fitness goals.

  20. McKinney

    I never imagined I could feel this energized and focused all day. This bundle has completely changed my routine. The lozenges give a quick boost—just pop one in and go. I use the powder before workouts, and my endurance has skyrocketed—I can push harder without feeling drained. Using both products together is so convenient, and the results are amazing.

  21. Max Robin

    N1o1 has saved my life. After listening to over 19 hours of Dr. Nathan’s videos I realized was not producing NO at all the. very first thing after using this bundle, I noticed that I could breathe. I may be ill but I felt that I was dying. Now I don’t and have so much faith in this wonderful ✨️ 💖 💕 product Amen

  22. Debbie p

    Love these products! Especially pre long bike rides

  23. Emilia Grasso

    This Nitric Oxide Booster Bundle has completely changed my mornings for the better

  24. Diana Snyder

    This bundle is 5 stars! More energy, better workouts, better life

  25. David McNulty

    Hi Dr. Bryan. That’s exactly what I have been doing since we met at the biohackers convention. I take the No Beets shot in the morning followed by the tablet boost in the late afternoon. I have more energy, think clearer, have been able to bump my workout routine, and have experienced a marked increase in focus and mental health. Next step, partner with you on my journey to create a healthier state for all my holistic health patients and clients!

  26. Emily Clark

    This is incredible. Stimulant-free and still powerful

  27. Vince

    My energy levels have been amazing. My workouts are better than before.

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