Susan K. Shaffer stands out as one of the most influential women driving the longevity and biohacking movement in 2025. As Co-Founder and President of N1O1 by Pneuma Nitric Oxide, she blends more than 30 years of corporate leadership with a deep commitment to science-driven wellness. Her background spans global brands like Lancôme, Dell, 3COM, and HumanN, giving her a unique ability to scale mission-focused companies and position them for rapid impact.
Her journey into nitric oxide began alongside Dr. Nathan Bryan, whose research shaped her passion for evidence-based health optimization. Today, Susan K. Shaffer leads N1O1 with a clear focus: unlocking the full therapeutic and performance potential of nitric oxide through proprietary technology and powerful IP. She believes nitric oxide is a “miracle molecule” capable of transforming human health, and she is committed to bringing that promise to the world.
In an era where longevity is less about lifespan and more about healthspan, Susan K. Shaffer’s work is pushing the industry forward. Her leadership fuels breakthroughs in nitric oxide science, performance enhancement, wellness innovation, and the growing global conversation around human potential. Among this year’s Top 20 Women Leading Biohacking & Longevity, she represents the perfect intersection of vision, execution, and transformative impact.