Why N1o1 Lozenges Are the #1 Nitric Oxide Supplement on the Market
When it comes to nitric oxide (NO) supplements, the market is full of options—from L-arginine to beetroot powders, multivitamins to performance blends. Yet none rival the effectiveness, speed, and scientific foundation of N1o1 Lozenges. Created by world-renowned nitric oxide researcher Dr. Nathan S. Bryan, N1o1 delivers real nitric oxide directly into the mouth with unmatched precision and speed. The result? Fast-acting, predictable vasodilation and a measurable improvement in blood flow, energy, and vitality.
Let’s explore why N1o1 is the clear leader, backed by over 25 years of research, peer-reviewed studies, and real-world results.
The Nitric Oxide Problem: Declining Production with Age
Nitric oxide is a critical molecule for cardiovascular health, circulation, immune function, and even sexual performance. However, as we age, our ability to produce NO declines. This is largely due to the diminishing function of an enzyme called nitric oxide synthase (NOS). This enzymatic pathway is what traditional supplements like L-arginine and L-citrulline rely on.
If your NOS system is compromised—due to age, stress, diet, inflammation, or metabolic conditions—then NO precursors like L-arginine are ineffective. Studies show that over 40% of adults over age 40 have impaired NO production and do not respond to traditional supplements.
Why Most NO Supplements Fail
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L-arginine: Requires conversion via NOS, which often fails in aging populations
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L-citrulline: Converted back to arginine before needing NOS again
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Beetroot: Relies on nitrate conversion by oral bacteria, which varies widely by individual
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Multivitamins: Supportive but do not directly produce nitric oxide
The bottom line: these supplements can help, but only if your body’s internal machinery is working perfectly. For many people, it’s not.
N1O1’s Breakthrough: Non-Enzymatic NO Delivery
N1o1 Lozenges are revolutionary because they do not depend on NOS enzymes or oral bacteria. Instead, they use a patented chemical reaction in the mouth to generate nitric oxide gas in real-time.
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Oral disintegrating lozenge
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Delivers NO gas directly through the oral mucosa
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No need for enzymatic pathways
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Effective regardless of age or health status
This is not just theory. It’s been validated in clinical trials showing rapid NO spikes, improved flow-mediated dilation, and better blood pressure control.
Fast, Predictable, and Measurable Results
Unlike traditional supplements that take weeks to work (if at all), N1O1 begins working in minutes.
| Supplement Type | Onset Time | Enzyme Dependent | Measurable NO Output | Side Effects |
|---|---|---|---|---|
| L-arginine / L-citrulline | Weeks | Yes | Variable | GI issues, headaches |
| Beetroot | Days to weeks | Yes (bacteria) | Unpredictable | GI distress |
| Multivitamin | Weeks | No | Indirect | Minimal |
| N1O1 Lozenges | <20 mins | No | Yes | Minimal (rare) |
The Science Behind N1o1
The creator of N1o1, Dr. Nathan S. Bryan, is a global authority on nitric oxide biology. He has published over 100 scientific papers and helped write the book on NO function.
N1o1 Lozenges use a proprietary formula that combines:
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Nitrite (a precursor to nitric oxide)
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A Reductant (to trigger the chemical reaction)
When mixed with saliva, the reaction produces NO gas on contact. This gas is then absorbed directly through the tissues of the mouth and into circulation.
Clinical Benefits Backed by Science
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Improved blood pressure and vascular tone
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Enhanced blood flow and oxygen delivery
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Better endothelial function
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Support for erectile function in aging men
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Increased athletic stamina and faster recovery
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Improved cognitive clarity and mood
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Anti-aging skin benefits through microcirculation
User Experience and Real Results
Thousands of users report tangible results:
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“I felt tingling and warmth within 15 minutes.”
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“My workouts are stronger, and I recover faster.”
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“By week two, my blood pressure had dropped significantly.”
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“It’s the first supplement that actually works for my ED.”
Testimonials like these back up the lab data.
Safety and Manufacturing Standards
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GMP-Certified Production Facility
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GRAS-Designated Ingredients
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Free of allergens, gluten, soy, and heavy metals
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IRB-approved safety studies completed
The lozenge formulation is stable, rigorously tested, and independently verified.
Who Should Use N1o1 Lozenges?
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Adults over 40 with declining vascular health
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Athletes looking for stimulant-free endurance
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People with poor circulation or ED
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Anyone frustrated by L-arginine or beetroot products
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Those seeking better brain, skin, or heart health
How to Take It
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Use one lozenge twice per day
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Let it dissolve slowly in the mouth (do not chew or swallow)
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Take on an empty stomach for best results
Many users report benefits beginning in just a few days, with optimal improvements within 2-4 weeks.
Why Dr. Bryan’s Work Matters
Dr. Bryan’s work is not only scientific, but transformational. He’s published on PubMed, spoken on YouTube, and developed clinical technologies that have changed the field of cardiology and aging.
His approach doesn’t rely on your body working perfectly. Instead, it bypasses what’s broken and replaces what’s missing—a key distinction from 99% of the supplement world.
Comparative Chart: Where N1o1 Wins
| Category | L-Arginine / L-Citrulline | Beetroot Powders | N1O1 Lozenges |
|---|---|---|---|
| Requires Enzymes | Yes | Yes | No |
| Onset Time | Weeks | Days to Weeks | <20 minutes |
| Efficacy in Aging | Poor | Variable | High |
| Side Effects | GI, headaches | GI, nausea | Rare (mouth tingling) |
| Clinically Measured NO | Inconsistent | Unpredictable | Yes |
| Founder is Scientist | No | No | Yes – Dr. Bryan |
Where to Buy N1O1
You can purchase directly from the N1o1 website
Subscription options and bundles are available for convenience and savings.
Final Word: N1o1 Is the Future of NO Supplementation
If you want a nitric oxide supplement that works fast, works reliably, and works for everyone—N1o1 is your answer. It’s clinically backed, real-time measurable, and free from the common drawbacks of old-school NO boosters.
Whether you’re aiming for better blood pressure, more energy, enhanced performance, or just a longer, healthier life, N1o1 Lozenges are the most advanced solution on the market today.
Helpful Links
Want to learn more? Follow Dr. Bryan’s research and explore the science behind real nitric oxide therapy at N1o1.com.
