Independence from Disease: Biohacker or Physician?
Happy 250th Birthday to the greatest nation on Earth. As we celebrate Independence Day and reflect on our freedoms here in the U.S.A., I could not help but think about people who are sick or in really bad health who cannot enjoy the freedoms afforded to us because of their illnesses. Americans are some of […]
Dr. Nathan Bryan Featured in Top Doctor Magazine
Dr. Nathan Bryan’s 25 years of nitric oxide research just got a major spotlight in Top Doctor Magazine The July 2026 issue features Dr. Bryan on the cover and an in-depth feature on his work on the science behind nitric oxide, why its decline drives nearly every age-related chronic disease, and how N1o1 products are changing […]
Nitric Oxide Drinks: 4 That Directly Boost Your Levels
The 4 best nitric oxide drinks, reviewed by a molecular medicine researcher. Beet juice, green juice, pomegranate, and watermelon, plus the habits that drain nitric oxide.
Best Nitric Oxide Supplements for Men and ED
The best nitric oxide supplements for men and ED, reviewed by a molecular medicine researcher. Top picks for blood flow, plus a critical safety note on ED medication.
Best Nitric Oxide Supplements: How to Choose One That Works
The best nitric oxide supplements, compared by a molecular medicine researcher. See our top picks, how to choose, and why the delivery pathway matters more than the label.
Why Your Fluoride Toothpaste Could Be Destroying Your Heart Health
Why Your Fluoride Toothpaste Could Be Destroying Your Heart Health The nitric oxide science your dentist was never taught — and the daily protocol that changes everything. NITRIC OXIDE SCIENCE • CARDIOVASCULAR HEALTH • ORAL MICROBIOME By Dr. Nathan S. Bryan, PhD | International Expert in Nitric Oxide Biochemistry & Founder N1o1 Most people […]
Risk Benefit of Sunlight Exposure vs Sunscreen
June marks the beginning of Summer in the Northern Hemisphere and a time when people hit the beach, enjoy the great outdoors and take vacations. Sunlight exposure has known health benefits that are indisputable. However, some people can overdo it can get sun burned. So how do we manage sun exposure and balance the health […]
The Gift of Health for Women and Mothers
Every second Monday of May we celebrate Mothers’ Day. Should not be surprising to you that this month, I address women’s health and highlight how we can and must improve women’s health. It is safe to say that none of us would be here without our mothers. They conceived us, carried us for nine months, […]
Hormesis: Joy in Pain and Suffering
Hormesis is a word that describes how brief periods of stress can lead to benefit from adaptation to the stress. This is a relatively new concept in science but is an ancient concept in religion and spirituality. There is a rich science demonstrating that brief periods of exercise, fasting, heat exposure, cold exposure, etc induces […]
Why L-Arginine Nitric Oxide Supplements Don’t Work After 40 (And What Does)
Understanding the L-Arginine Nitric Oxide Pathway The *L-arginine nitric oxide* pathway is a well-documented mechanism where the enzyme endothelial nitric oxide synthase (eNOS) converts L-arginine into nitric oxide (NO) within blood vessel walls. This process, known as the “L-arginine-NO pathway,” effectively boosts NO production in young, healthy individuals with optimal eNOS function. In these individuals, […]