Why N1o1 Lozenges Are the #1 Nitric Oxide Supplement

Why N1o1 Lozenges Are the #1 Nitric Oxide Supplement 

Why N1o1 Lozenges Are the #1 Nitric Oxide Supplement

N1o1 Lozenges are the top nitric oxide supplement, outperforming L-arginine and L-citrulline by delivering NO directly in the mouth (enzyme-independent), resulting in fast (<20 min), predictable vasodilation with minimal side effects. Supported by 25+ years of Dr. Nathan S. Bryan’s research, clinical trials show improved circulation, blood pressure, athletic performance, cognitive focus, and sexual health. Safe, GMP-manufactured, and effective across all ages, N1o1 sets a new standard in NO supplementation.

When it comes to enhancing nitric oxide (NO) levels safely and effectively, no product compares to N1o1 Lozenges. Developed by world-renowned nitric oxide expert Dr. Nathan S. Bryan, N1o1 delivers fast, predictable results that significantly surpass traditional supplements like L-arginine or L-citrulline.

5e1c8a93c30ba87384b76cfcbd4cc2c122d7016bfc21f36a6521d5d3a6240edf-300x300.png

  1. Meet the Scientist Behind the Science
    N1o1 was born from over 25 years of nitric oxide research by Dr. Nathan S. Bryan, a pioneer in NO biology. Explore the breakthrough in our blog post, Scientific Breakthrough in Nitric Oxide Delivery, and see how Dr. Bryan’s work laid the groundwork. His dedication ensures GMP-quality manufacturing and clinically proven efficacy.
  2. Why Precursors Fall Flat: L-Arginine vs. N1o1
    L-Arginine depends on nitric oxide synthase (NOS), which deteriorates with age, making its effects inconsistent.
    L-Citrulline offers better absorption but still relies on NOS and demands high, daily intake.
    N1o1 Lozenges generate nitric oxide directly in the mouth, bypassing enzymatic limitations entirely. This guarantees rapid vasodilation regardless of age or endothelial health.
  3. Innovative Lozenge-Based Delivery
    N1o1’s breakthrough lozenge technology includes:
  • A nitrite + reductant formula for controlled NO production via saliva.
  • Immediate, measurable NO release in seconds—not hours or days.
  • Zero digestive distress due to bypassing the gastrointestinal tract.

Clinical studies confirm increased salivary and exhaled NO, improved flow-mediated dilation, and lowered blood pressure—markedly outperforming L-arginine.

  1. #1 in Clinical Effectiveness
    Extensive human trials highlight N1o1’s advantages:
  • Rapid NO elevation versus the slow or negligible gains from precursors.
  • Significant improvements in endothelial health, microcirculation, and blood pressure.
  • Efficacy even in NOS-impaired populations such as aging adults or those with metabolic conditions.

  1. Comprehensive Health Benefits
    Beyond ED and vascular health, N1o1 supports:
  • Cardiovascular performance (enhanced oxygen uptake, heart function).
  • Athletic endurance and recovery.
  • Cognitive clarity through improved neurovascular coupling (see Dr. Bryan’s talk on YouTube).
  • Skin health, benefiting collagen and circulation.

In contrast, L-arginine, L-citrulline, and nutrient blends often deliver inconsistent results.

  1. Fast-Acting, Sustained, and Predictable
  • Rapid onset: Users report warmth or tingling within minutes.
  • Short-term improvements: Circulation and energy boost within days.
  • Long-term results: Sustained vitality and cardiovascular health within weeks.
  • Reliable across ages, especially where precursors like L-arginine fail.

  1. Safe, Tested & Transparent
  • Manufactured from GRAS-certified ingredients in a GMP-certified facility.
  • Supported by IRB-approved safety studies, with minimal side effects (e.g., mild dizziness or mouth tingling).
  • No fillers, allergens, or heavy metals—unlike many precursor-based blends.

  1. The Competitive Edge
    | Supplement Type            | Efficacy            | Onset     | Safety          | Experience               |
    |––––––––––––––|———————|———–|——————|–––––––––––––|
    | L-Arginine / L-Citrulline | Variable, age-dependent | Weeks     | GI issues        | Only in healthy users    |
    | Beetroot / Multivitamins  | Supportive (deficient-dependent) | Weeks+    | Generally safe    | Modest benefits          |
    | Performance NO Blends     | Mixed, bulk doses    | Days–Weeks | Dose-related side effects | Inconsistent results     |
    | N1o1 Lozenges             | High, predictable    | <20 mins  | Low side-effects  | Immediate vitality & flow |

N1o1’s enzyme-free, clinically validated technology makes it the clear leader.

  1. Quick Links For Product Info
  1. Real Testimonials: Real Proof
    “I tried L-arginine—nothing. With N1o1, effects were immediate.” – Verified user
    “Energy and blood flow improved by day 3; by week 2, I felt 10 years younger.”
    These anecdotes reinforce scientific data and highlight N1o1’s potency.
  2. Expert Opinions
  • BannerHealth confirms NO’s importance for vascular health independent of precursor variability.
  • Experts at Verywell Health stress the limitations of precursor supplements and cite direct-mouth NO delivery as emerging best practice.
  • Men’s Health acknowledges that many NO products rely on precursors and have inconsistent results.

Their take aligns perfectly with N1o1’s evidence-backed performance.

  1. How to Use N1o1 for Best Results
    Recommended Routine:
  • Take one lozenge twice daily, preferably on an empty stomach.
  • Let the lozenge dissolve completely in the mouth—don’t swallow it whole.
  • Notice immediate effects: tingling, warmth, or cognitive alertness.
  • Track key health markers: circulation, energy, mood, skin vitality.

Enhancements:

  • Pair with a nitrate-rich diet (e.g., beets, leafy greens).
  • Exercise regularly to further boost NO production.
  • Use deep breathing or meditation to support overall vascular health.
  1. Founder’s Vision
    Dr. Bryan explains: “Most nitric oxide products depend on your body working perfectly. Ours doesn’t.”
    N1o1’s non-enzymatic design ensures it works even when NOS pathways are compromised.
  2. Availability & Where to Buy
  • Purchase N1o1 Lozenges on the official product page.
  • Also available in trusted retailers such as Amazon.
  • Look out for bundle deals and subscription options for easy reordering.
  1. Final Takeaways
    If you’re searching for the top nitric oxide supplement, N1o1 Lozenges stand unmatched:
  • Fast-acting (<20 min)
  • Clinically validated results
  • Doctor-formulated, transparent ingredients
  • Minimal side effects

N1o1 is not “just another NO pill”—it’s a scientifically robust, enzyme-independent tool for real, measurable health improvements.

Picture of Dr. Nathan S Bryan, Ph.D.

Dr. Nathan S Bryan, Ph.D.

Dr. Bryan Ph.D is the worlds foremost Researcher of Nitric Oxide. International Leader in Molecular Medicine. Founder of Bryan Therapeutics,Inc., Nitric Oxide Innovations, LLC, N1o1.com, and Bryan Nitriceuticals (No2U.com) SEE FULL BIO